Fri, Sep 20, 2024
Volume 10, Issue 2 (12-2021)
ABS 2021, 10(2): 93-98 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Malekpour Alamdari N, Zeinalpour A, hosseinipour F, Kimia F, gholizadeh B. Evaluation Effects of Sleeve Gastrectomy to Bone Metabolism and Bone Mineral Densitometry in Patients Over 50 Years. ABS 2021; 10 (2) : 7
URL: http://annbsurg.iums.ac.ir/article-1-325-en.html
URL: http://annbsurg.iums.ac.ir/article-1-325-en.html
Nasser Malekpour Alamdari1 
, Adel Zeinalpour1 , Forough Hosseinipour1 , Fereshteh Kimia2 , Barmak Gholizadeh 1
, Adel Zeinalpour1 , Forough Hosseinipour1 , Fereshteh Kimia2 , Barmak Gholizadeh 1
1- Department of General Surgery, shahid Modarres hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Clinical Research Development Center, Shahid Modarres Educational hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2- Department of anesthesiology, labbafinezhad hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2- Department of anesthesiology, labbafinezhad hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract: (622 Views)
Background: Despite the improvement in health, function and quality of life of patients with morbid obesity following bariatric surgery, such intervention may result in some potential complications such as metabolic disturbances especially involving bone motabolism. The aim of this study was to evaluate the extent of Bone Mineral Density (BMD) changes in older patients with morbid obesity and its relation with bone metabolism indices.
Methods: This study was a single-center cross-sectional study on 50 new morbidly obese patients over 50 years old of age who were candidates for bariatric surgery. Before and 6 months after surgery, the values of BMD, anthropometric indices and metabolic serum biomarkers were assessed.
Results: BMD examination before and 6 months after surgery showed decrease in the BMD in hip region from 1.242 ± 0.136 to 1.117 ± 0.112 g/cm2, in the femoral neck from 1.109 ± 0.131 to 0.987 ± 0.127 g/cm2, in the lumbar spine from 1.253 ± 0.146 to 1.190 ± 0.135 g/cm2. The analysis of BMD changes showed significant decrease in the bone density of all site measurement but with variable amounts. The decrement of BMD in the hip and femoral neck was significant but in the spine was not significant. The analysis on bone metabolism markers showed significant increase in 25-Hydroxy vitamin D and Alkaline phosphatase levels but decrease in calcium and parathyroid hormone (PTH) during 6 month follow up.
Conclusion: There is significant decrease in BMD at various skeletal areas including femoral neck and hip region. Such changes can be in line with the changes in some serum metabolic and hormonal biomarkers such as calcium, PTH, vitamin D and alkaline phosphatase.
Methods: This study was a single-center cross-sectional study on 50 new morbidly obese patients over 50 years old of age who were candidates for bariatric surgery. Before and 6 months after surgery, the values of BMD, anthropometric indices and metabolic serum biomarkers were assessed.
Results: BMD examination before and 6 months after surgery showed decrease in the BMD in hip region from 1.242 ± 0.136 to 1.117 ± 0.112 g/cm2, in the femoral neck from 1.109 ± 0.131 to 0.987 ± 0.127 g/cm2, in the lumbar spine from 1.253 ± 0.146 to 1.190 ± 0.135 g/cm2. The analysis of BMD changes showed significant decrease in the bone density of all site measurement but with variable amounts. The decrement of BMD in the hip and femoral neck was significant but in the spine was not significant. The analysis on bone metabolism markers showed significant increase in 25-Hydroxy vitamin D and Alkaline phosphatase levels but decrease in calcium and parathyroid hormone (PTH) during 6 month follow up.
Conclusion: There is significant decrease in BMD at various skeletal areas including femoral neck and hip region. Such changes can be in line with the changes in some serum metabolic and hormonal biomarkers such as calcium, PTH, vitamin D and alkaline phosphatase.
Article number: 7
Keywords: sleeve gastrectomy, bone mineral density, calcium, vitamin D, parathyroid hormone, metabolism
Type of Study: Original |
Subject:
Sleeve Gastrectomy
Received: 2021/11/16 | Accepted: 2021/12/23 | ePublished: 2022/03/16
Received: 2021/11/16 | Accepted: 2021/12/23 | ePublished: 2022/03/16
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
