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Volume 9, Issue 2 (Annals of Bariatric Surgery 2020)
ABS 2020, 9(2): 1-8 |
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Safari S, Samadi Afshar A, Alemrajabi M, Baghai Wadji M, Hashemi Madani N. Therapeutic effects of obesity surgery on glucose control in patients with type 2 diabetes. ABS 2020; 9 (2) :1-8
URL: http://annbsurg.iums.ac.ir/article-1-274-en.html
URL: http://annbsurg.iums.ac.ir/article-1-274-en.html
Saeed Safari1 
, Amir Samadi Afshar 1, Mahdi Alemrajabi1 , Massoud Baghai Wadji1 , Nahid Hashemi Madani2
, Amir Samadi Afshar 1, Mahdi Alemrajabi1 , Massoud Baghai Wadji1 , Nahid Hashemi Madani2
1- Department of General Surgery, School of Medicine, Firoozgar General Hospital, Iran University of Medical Sciences, Tehran , Iran
2- Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
2- Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
Abstract: (897 Views)
Background: Obesity is considered as an independent risk factor for type 2 diabetes (T2D) and other metabolic diseases. Obesity accounts for about 55% of diabetes. This study aimed to investigate the therapeutic effects of obesity surgery on glucose, HbA1C, insulin and C-peptide serum levels in the patients with T2D.
Methods and materials: This prospective cohort study carried out on 25 patients aged between 18-70 years who had with T2D and body mass index above 40 kg /m2. Fasting blood sugar (FBS) level, HbA1C and Two-hour postprandial (2HPP), insulin level, and C-peptide were measured in all patients before surgery and the patients were fully evaluated for the presence of diabetes complications. The patients underwent Roux-en-Y Gastric Bypass (RYGB), mini-gastric bypass, and sleeve gastrectomy, and were re-evaluated 24 hours, one week, two month, and six months after surgery.
Results: Twenty-five people underwent (sleeve gastrectomy for 12 cases, RYGB for 7 cases and mini-bypass surgery for 6 cases). Twenty cases (80.0%) were women and five cases (20.0%) were men. The mean age of the patients was 46.16 ± 10.97 years (25-67 years).The mean fasting blood sugar, 2HPP, HbA1C, insulin, and C-peptide in general and in all three groups showed a significant decrease.
Conclusion: The findings of the study showed that all three surgical procedures were effective in improving T2D by six months after surgery.
Methods and materials: This prospective cohort study carried out on 25 patients aged between 18-70 years who had with T2D and body mass index above 40 kg /m2. Fasting blood sugar (FBS) level, HbA1C and Two-hour postprandial (2HPP), insulin level, and C-peptide were measured in all patients before surgery and the patients were fully evaluated for the presence of diabetes complications. The patients underwent Roux-en-Y Gastric Bypass (RYGB), mini-gastric bypass, and sleeve gastrectomy, and were re-evaluated 24 hours, one week, two month, and six months after surgery.
Results: Twenty-five people underwent (sleeve gastrectomy for 12 cases, RYGB for 7 cases and mini-bypass surgery for 6 cases). Twenty cases (80.0%) were women and five cases (20.0%) were men. The mean age of the patients was 46.16 ± 10.97 years (25-67 years).The mean fasting blood sugar, 2HPP, HbA1C, insulin, and C-peptide in general and in all three groups showed a significant decrease.
Conclusion: The findings of the study showed that all three surgical procedures were effective in improving T2D by six months after surgery.
Type of Study: Original |
Subject:
Gastric Bypass
Received: 2021/01/4 | Accepted: 2021/02/17 | ePublished: 2021/02/18
Received: 2021/01/4 | Accepted: 2021/02/17 | ePublished: 2021/02/18
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