en MIS MIS Original Original Background: Small bowel obstruction is one of the most common surgical emergencies and main causes of hospital admissions. Diatrizoate Meglumine Gastrografin, a hyperosmolar water-soluble contrast agent, has been used to triage patients with small bowel obstruction for an operative or a non-operative management. It can also have a therapeutic effect by increasing the pressure gradient across obstructive sites that may result in resolving the obstruction. Objectives: The aim of this study was to test the gastrografin effect in the resolution of small bowel obstruction. Patients and Methods: In this cross sectional–descriptive study, gastrografin was given to patients diagnosed with small bowel obstruction in clinical and radiological grounds . The contrast passage was assessed by serial X-rays. If the contrast remained in the small bowel, a decision was made as to whether proceed to surgical intervention, based on clinical condition. The patients were divided into two groups: A, who finally required surgery, and B, who were resolved by gastrografin administration. Results: Forty six patients were entered into the study. Thirty seven of the patients (80%) received a non-operative course in whom the contrast was observed in the large bowel. They had a mean hospital stay of 4.6 days. Nine patients (20%) required operative intervention. These patients had a mean hospital stay of 8 days. Conclusions: This study has demonstrated that gastrografin was highly effective in the management of adhesive small bowel obstruction resulting in a decreased need for surgery and hospital stay. Diatrizoate Meglumine Intestinal Obstruction Surgery 0 0 http://annbsurg.iums.ac.ir/browse.php?a_code=A-10-31-252&slc_lang=en&sid=1 Sina Safamanesh 1003194753284600804 1003194753284600804 No 1 Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, IR Iran Abdolreza Pazouki 1003194753284600805 1003194753284600805 No 1 Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, IR Iran Zeinab Tamannaie 1003194753284600806 1003194753284600806 Yes 1 Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, IR Iran Behnoush Mohammadalipour 1003194753284600807 1003194753284600807 No Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Koosha Ramezani 1003194753284600808 1003194753284600808 No Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Esmaeel Hajnasrollah 1003194753284600809 1003194753284600809 No Department of Surgery, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Ghazal Hajnasrollah 1003194753284600810 1003194753284600810 No Department of Surgery, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Shahla Chaichian 1003194753284600811 1003194753284600811 No 1 Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, IR Iran 4 Faculty of Medicine, Islamic Azad University, Tehran Medical Branch, Tehran, IR Iran