en High Prevalence of Zinc Deficiency in Iranian Morbid Obese Patients Undergoing Bariatric Surgery Basic Science Basic Science Original Original <sec> <div>Background</div> <p>Bariatric surgery&amp;#x2019;s efficacy in morbid obesity therapy has been proven; but post-operational zinc deficiency is a problematic issue as its essential role in post-operational recovery of patients.</p> </sec> <sec> <div>Objectives</div> <p>The aim of this study is to evaluate the rate of zinc deficiency in Iranian morbidly obese candidates for bariatric surgery.</p> </sec> <sec> <div>Patients and Methods</div> <p>We assessed zinc status in 996 morbidly obese subjects (BMI &amp;gt; 40 kg/m² or BMI &amp;gt; 35 kg/m² with any comorbidities) (841 females, 155 males) who were candidate for bariatric surgery. Comorbidities related to obesity including dyslipidemia, abnormal fasting glucose, hypertension and type-2 diabetes (T2D) were evaluated. Also we checked albumin and SGPT as markers of liver function. Data analyzed by SPSS.</p> </sec> <sec> <div>Results</div> <p>Zinc deficiency was found in 13.6% of patients. Zinc levels had an inverse and significant association with age (P Value = 0.016). Although greater levels of circulating zinc were observed in patients with higher BMI, there were no significant correlation between zinc deficiency and adiposity. Dyslipidemia was found to be the most prevalent comorbidity in this population.</p> </sec> <sec> <div>Conclusions</div> <p>These results show a high prevalence of zinc deficiency in morbidly obese subjects. Thus, we suggest the evaluation of the zinc status in patients undergoing bariatric surgery and treatment of zinc deficiency before doing the surgery.</p> </sec> Prevalence,Zinc Deficiency,Morbid Obese,Bariatric Surgery 100 110 http://annbsurg.iums.ac.ir/browse.php?a_code=A-10-31-166&slc_lang=en&sid=1 Gholamreza Mohammadi Farsani 1003194753284600347 1003194753284600347 No Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, IR Iran Fateme Zabetian Targhi 1003194753284600348 1003194753284600348 No Department of Cellular and Molecular Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, IR Iran Mohadeseh Pishgahroudsari 1003194753284600349 1003194753284600349 No Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, IR Iran Somaye Mokhber 1003194753284600350 1003194753284600350 No Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, IR Iran Abdolreza Pazouki 1003194753284600351 1003194753284600351 Yes Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, IR Iran