en Laparoscopic Cholecystectomy: A Retrospective Four-Year Study Basic Science Basic Science Original Original <sec> <div>Background</div> <p>Today, laparoscopic cholecystectomy is considered as the gold standard treatment for cholecystectomy, which is mainly due to improved results of laparoscopic surgery compared to the open surgery, and its cosmetic benefits.</p> </sec> <sec> <div>Objectives</div> <p>The purpose of this study was to evaluate the results of laparoscopic cholecystectomy in our institution.</p> </sec> <sec> <div>Patients and Methods</div> <p>This is a retrospective study. Medical records of patients who underwent laparoscopic cholecystectomy from 2004 to 2008 were reviewed. The results and complications of surgery were collected using a checklist.</p> </sec> <sec> <div>Results</div> <p>Participants included 500 patients with mean age of 47 &amp;#xB1; 11 years. Three hundred ninety-one (78.2%) were female and 109 (21.8%) were male. Four hundred (80.0%) of patients had symptomatic cholelithiasis. The mean operating time was 70 &amp;#xB1; 8 minutes. The most common intra-operative complication was bradycardia during gas insufflation into the abdominal cavity. In 430 (86.0%) of patients length of hospital stay was less than two days. Six patients (1.2%) were complicated by hernia at incision site, 18 (3.6%) by bile leakage, and 15 (3.0%) required laparotomy. Surgical site bleeding and surgical site infection were observed respectively in 11 patients (2.2%) and 17 patients (3.4%). Totally, 52 patients (10.4%) had surgically-induced complications, two (0.4%) of whom died.</p> </sec> <sec> <div>Conclusions</div> <p>Laparoscopic cholecystectomy as the method of choice in treatment of gallbladder stone is associated with high success rate. This approach is increasingly being performed because of the decrease in patients&amp;#x2019; hospital stay, morbidity, and rapid return to normal life.</p> </sec> Cholelithiasis,Cholecystectomy,Complications 100 110 http://annbsurg.iums.ac.ir/browse.php?a_code=A-10-31-157&slc_lang=en&sid=1 Mohammad Taghi Rajabi Mashhadi 1003194753284600308 1003194753284600308 No Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran Abbas Abdollahi 1003194753284600309 1003194753284600309 No Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran Alireza Tavassoli 1003194753284600310 1003194753284600310 No Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran Mohammad Naser Forghani 1003194753284600311 1003194753284600311 No Hossein Shabahang 1003194753284600312 1003194753284600312 No Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran Ehsan Keykhosravi 1003194753284600313 1003194753284600313 No Azadeh Jabbari Nooghabi 1003194753284600314 1003194753284600314 No Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran Reza Rezaei 1003194753284600315 1003194753284600315 Yes Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, IR Iran