en A Prospective Randomized Trial to Study The Effect of Intraperitoneal Instillation of Ropivacaine in Postoperative Pain Reduction in Laparoscopic Cholecystectomy Basic Science Basic Science Original Original <sec> <div>Background</div> <p>Postoperative pain following laparoscopic cholecystectomy can be due to various reasons. In this study reduction of visceral and shoulder tip pain is studied with intra peritoneal instillation of ropivacaine.</p> </sec> <sec> <div>Objectives</div> <p>The study was done to see the effect of intraperitoneal instillation of ropivacaine on postoperative abdominal pain and shoulder pain in laparoscopic cholecystectomy.</p> </sec> <sec> <div>Patients and Methods</div> <p>Sixty patients with symptomatic gall stone diseases undergoing laparoscopic cholecystectomy were randomized into two groups. In study group A (n = 30 patients) 0.5% of 30 mL (150 mg) of ropivacaine, and in control (placebo) group B (n = 30) 30 mL of normal saline was instilled in the gall bladder bed.</p> </sec> <sec> <div>Results</div> <p>Abdominal pain is worse during the first 24 hours after laparoscopic cholecystectomy. After 6 and 12 hours abdominal pain was significantly less in group A compared to group B (P &amp;lt; 0.035). Group A experienced less shoulder tip pain during the first postoperative day, compared to control group.</p> </sec> <sec> <div>Conclusions</div> <p>Intraperitoneal instillation of ropivacaine is more effective than placebo instillation at early postoperative hours in reducing postoperative abdominal pain after laparoscopic cholecystectomy.</p> </sec> Laparoscopy,Cholecystectomy,Pneumoperitoneum,Pain,Ropivacaine 100 110 http://annbsurg.iums.ac.ir/browse.php?a_code=A-10-31-149&slc_lang=en&sid=1 Pankaj Shivhare 1003194753284600275 1003194753284600275 No Department of Surgery, All India Institute of Medical Sciences, New Delhi, India Pankaj Dugg 1003194753284600276 1003194753284600276 Yes Department of Surgery, All India Institute of Medical Sciences, New Delhi, India Harnam Singh 1003194753284600277 1003194753284600277 No Department of General Surgery, Government Medical College, Patiala, India Sushil Mittal 1003194753284600278 1003194753284600278 No Department of General Surgery, Government Medical College, Patiala, India Ashwani Kumar 1003194753284600279 1003194753284600279 No Department of General Surgery, Government Medical College, Patiala, India Anand Munghate 1003194753284600280 1003194753284600280 No Department of General Surgery, Government Medical College, Patiala, India